German Partners

BG Klinikum Bergmannstrost 


The BG Klinikum Bergmannstrost Halle is a specialized hospital for the treatment of severe injured patients and the treatment of musculoskeletal disorders in general. The hospital has a population responsibility for around 2.0 million inhabitants in central Germany. The main focuses of the Department of Neurosurgery are the treatment of spinal disorders by degeneration, injuries and tumours and the operative treatment of the brain including trauma, bleeding, tumour and vascular disorders. 
The infrastructure includes state-of-the art operating theatres, a musculoskeletal imaging unit and has thereby the necessary facilities and equipment for the implementation of the project. The BG Klinikum Bergmannstrost Halle are well connected with the faculties of medicine of the Universities of Halle, Jena and Leipzig, and their researchers work in close connection to the Translational Centre for Regenerative Medicine (TRM) and University of Applied Sciences (HTWK), Innovative Surgical Training Technologies (ISTT) in Leipzig and Fraunhofer Institute for Cell Therapy and Immunology (IZI) and Fraunhofer Institute for Mechanics of Materials (IWM). BG-BMT is active in a great variety of research fields, including diagnostic imaging, tissue engineering, materials science, cell therapies and clinical trials. Between 2002 and 2007 BG-BMT was principle investigator for the EURODOSIC multicentre trail. In the study patients underwent an autologous disc cell transplantation after sequestrectomy. Since 2012 BG-BMT is principle investigator in the international, multicenter NDisc TETEC trail, an autologous disc cell transplantation with preformated hydrogel.



Team composition


Prof.  Hans Jörg Meisel, MD PhD


Is primary focused on spine surgery and research for the last 20 years in degenerative spinal diseases. Starting as an inventor and designer of spinal implants for the inter-vertebral space in cervical and lumbar in arthroplasty and fixation he developed 1997 the first biological disc repair transplantation system with autologus chondrocytes. Furthermore his research is focused in the biomechanical mechanical characterisation of spinal implants. Due to the connection with TRM, HTWK, ISTT, IZI and IWM there is a great experience to develop new surgical instruments, procedures and testing them in clinical studies. He is also a member of the AO Knowledge degenerative and biologics. He is this partner’s scientific advisor and scientific coordinator and will treat and follow-up the 12 - 15 patients in the clinical study. He serves on the Executive Board – AOSpine Knowledge Forum Degenerative and Biologics



Stefan Bone, MD


Is a specialist registrar neurosurgeon at the Department of Neurosurgery - BG Klinikum Bergmannstrost Halle. He has extensive experience in general spine surgery including clinical application of autologous disc cell transplantation procedures. He will operate the patients in the clinical phase one study. Together with the study coordinators/ study nurses, he directs the design office and organizes conferences and workshops. 



Herrmann Esther, 


Has completed a training as nurse with over 10 years of ICU experience and has an additional training as study nurse. She has  8 years of experience as study nurse.



Minkus Yvonne,


Has completed a training as a nurse with more than 17 years of professional experience. She has participated in various publications based on her more than 10 years of experience as study nurse and qualifications.


Peruth-Stutzmann Lydia, 


Manages the legal department and ensures the conformity of the clinical study with European law and patient’s rights.






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